Starting SPINRAZA/Find a Treatment Center

There are SPINRAZA treatment centers all across the US1

SPINRAZA is administered as an intrathecal injection by a medical provider able to perform lumbar punctures.2

*Required field.

OR

Please note that new centers are added regularly and may not be in this locator tool yet. For additional treatment centers,
please call us at 1-844-4SPINRAZA (1-844-477-4672).

Refine your search. Show centers that:

Results Found

Find a treatment center

Enter your location above to find a treatment center.

Biogen does not receive payment for this service and does not endorse or recommend any treatment facilities that have chosen to be listed. Further, Biogen does not have oversight of and is not responsible for the actions of any treatment center.

Biogen does not guarantee availability at any particular treatment center. Every individual is unique, and only after careful medical evaluation can a course of treatment be determined.

SPINRAZA is an intrathecal injection given 3 times a year after 4 initial doses2

Learn about dosing & administration
HEAR FROM PATIENTS ON THERAPY

INDICATION

SPINRAZA is indicated for the treatment of spinal muscular atrophy (SMA) in pediatric and adult patients.

IMPORTANT SAFETY INFORMATION

Coagulation abnormalities and thrombocytopenia, including acute severe thrombocytopenia, have been observed after administration of some antisense oligonucleotides. Patients may be at increased risk of bleeding complications.

In the sham-controlled studies for patients with infantile-onset and later-onset SMA, 24 of 146 SPINRAZA-treated patients (16%) with high, normal, or unknown platelet count at baseline developed a platelet level below the lower limit of normal, compared to 10 of 72 sham-controlled patients (14%). Two SPINRAZA-treated patients developed platelet counts <50,000 cells per microliter, with the lowest level of 10,000 cells per microliter recorded on study day 28.

Renal toxicity, including potentially fatal glomerulonephritis, has been observed after administration of some antisense oligonucleotides. SPINRAZA is present in and excreted by the kidney. In the sham-controlled studies for patients with infantile-onset and later-onset SMA, 71 of 123 SPINRAZA-treated patients (58%) had elevated urine protein, compared to 22 of 65 sham-controlled patients (34%).

Laboratory testing and monitoring to assess safety should be conducted. Perform a platelet count, coagulation laboratory testing, and quantitative spot urine protein testing at baseline and prior to each dose of SPINRAZA and as clinically needed.

Severe hyponatremia was reported in an infant treated with SPINRAZA requiring salt supplementation for 14 months.

Cases of rash were reported in patients treated with SPINRAZA.

SPINRAZA may cause a reduction in growth as measured by height when administered to infants, as suggested by observations from the controlled study. It is unknown whether any effect of SPINRAZA on growth would be reversible with cessation of treatment.

The most common adverse reactions (≥20% of SPINRAZA-treated patients and ≥5% more frequently than in control patients) that occurred in the infantile-onset controlled study were lower respiratory infection and constipation. Serious adverse reactions of atelectasis were more frequent in SPINRAZA-treated patients (18%) than in control patients (10%). Because patients in this controlled study were infants, adverse reactions that are verbally reported could not be assessed. The most common adverse reactions that occurred in the later-onset controlled study were pyrexia, headache, vomiting, and back pain. Post-lumbar puncture syndrome has also been observed after the administration of SPINRAZA.

Please see full Prescribing Information.

As a courtesy, our full Prescribing Information is also available en Español. For prescribing decisions, please refer to official approved labeling.

References

1. Biogen Data on File [as of 6/20]. 2. SPINRAZA. Prescribing Information. Biogen; 2023.

Stay Connected
Sign up with us to receive the latest news, support information, and upcoming events.

ABOUT SMA
What Is SMA Multidisciplinary Care
Why SPINRAZA
About SPINRAZA How SPINRAZA Works Presymptomatic Efficacy Early-Onset Efficacy Later-Onset Efficacy Real-World Evidence Safety
Starting SPINRAZA
How to Start Find a Treatment Center Dosing & Administration
Patients on Therapy
Patients on Therapy
Support
Access & Reimbursement SMA360°™ Patient Support Events

©2024 Biogen. All rights reserved.
This site is intended for US Healthcare Professionals only.
SPZ-US-3383 v10 05/24